General information about Amoxicillin in the UK
Combined broad-spectrum antibiotic that is resistant to the action of β-lactamases containing amoxicillin and clavulanic acid.
Amoxicillin - a semi-synthetic broad-spectrum antibiotic active against many gram-positive and gram-negative microorganisms. Amoxicillin being destroyed β-lactamases, so its spectrum antibacterial activity does not include microorganisms that produce β-lactamase.
Clavulanic acid - β-lactam compound has the ability to inactivate a wide range of β-lactamases, enzymes which ordinarily produce microbes that are resistant to penicillins and cephalosporins.
The presence of clavulanic acid in the Augmentin amoxicillin protects against the damaging action of β-lactamases and extends its spectrum of antibacterial activity with the inclusion of micro-organisms normally resistant to other cephalosporins and penicillins.